Costs Associated with the Treatment of Ig Adverse Drug Reactions

Costs Associated with the Treatment of Ig Adverse Drug Reactions

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Question 1 of 5

1. Question
1. A Serious or Severe Drug Reaction (ADR) is defined as:
- Intended response to a medicinal product
- A reaction that can result in a life-threatening event
- Hives and pruritis
- Mild headache
Question 2 of 5

2. Question
The following is true about ADRs and Ig:
- Can occur during any infusion
- Can vary between lot numbers
- Are antigen-antibody reactions
- Are a result of a blood reaction
Question 3 of 5

3. Question
It is important to pay attention to ADRs because:
- They account for 100,000 deaths yearly
- They cost about $200 million dollars annually
- The pharmacist and nurse are liable for any ADR
- They don’t usually cause death, but can be expensive to the consumer
Question 4 of 5

4. Question
Why we put a value on ADRs:
- We know that the most common ADRs are from Ig administration.
- ADRs account for 3.5 million physician office visits with estimated 1 million ER visits and 135,000 hospital admissions.
- Patients experience ADRs with all medications on the first or second lifetime dose
Question 5 of 5

5. Question
Intervention(s) to mitigate ADRs with IGiV:
- Evaluate the need for premedication and hydration
- Monitor vital signs at baseline and with every rate change throughout the infusion
- Limit daily dosage of Ig to 400-500mg/kg per day
- Slow infusion rates