Lesson 2: Autoinflammatory Disorders

Author:
Lori Broderick, MD, PhD 
Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of California-San Diego, La Jolla, CA
Rady Children’s Hospital San Diego, San Diego, CA 

OBJECTIVES 

1. Define autoinflammatory disorders 
2. Appreciate the role of phenotyping and family history in the diagnosis of autoinflammatory disease 
3. Describe the basis of inflammasome-mediated inflammation 
4. Describe the role of cytokine-targeting biologics as therapy for these disorders

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