Author: Lori Broderick, MD, PhD Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of California-San Diego, La Jolla, CA Rady Children’s Hospital San Diego, San Diego, CA
OBJECTIVES
Define autoinflammatory disorders
Appreciate the role of phenotyping and family history in the diagnosis of autoinflammatory disease
Describe the basis of inflammasome-mediated inflammation
Describe the role of cytokine-targeting biologics as therapy for these disorders