Lesson 1: Secondary Immune Deficiencies From Biological Agents Copy

Mark Ballow, MD
Professor of Pediatrics
Division of Allergy and Immunology
Morsani College of Medicine
University of South Florida St. Petersburg, Florida 


  1. Review the nomenclature for monoclonal antibodies 
  2. Understand the mechanisms for prolonged hypogammaglobulinemia with Rituximab 
  3. Review the immune and infectious consequences of some of the most frequently used biologics on the immune system 
  4. Review the adverse effects of immune checkpoint inhibitors